He married Martha Crouch. His parents were Isaac Denton and Ann Whitson.
Isaac and Martha's children included:
Anna Denton (1804, married Charles Reagan and Joseph Cathcart)
Isaac Denton (1805)
George Nolan Denton (1807, married Martha Crouch)
Tabitha H. Denton (1808)
Joseph Denton (1811)
Phoebe Denton (1813), and
Jeremiah Denton (1815)
Isaac Denton
Source: Will book No. 1, pg. 54
Wife - Ann
Children - Isaac, Jeremiah, Martha, Agnes, Elizabeth, Susannah
Executors - Jesse Whitson, David Job